Excretion of hydroxyurea into milk.
نویسندگان
چکیده
This article documents that hydroxyurea (HUR) is excreted into human breast milk, and it reviews the literature describing similar evaluations for other antineoplastic agents.
منابع مشابه
Excretion of Acebutolol and its Major Metabolite Diacetolol into Infant Blood Circulation and the Breast Milk
Acebutolol (AC) is a chiral b-adrenergic blocking drug, which is useful clinically as the racemate in treating hypertension and is metabolized to an equipotent chiral metabolite, diacetolol (DC). In this paper we report a case of a 32 year old woman who was receiving AC during her pregnancy and lactating time for management of hypertension. The maternal plasma level and breast milk as well as c...
متن کاملExcretion of Acebutolol and its Major Metabolite Diacetolol into Infant Blood Circulation and the Breast Milk
Acebutolol (AC) is a chiral b-adrenergic blocking drug, which is useful clinically as the racemate in treating hypertension and is metabolized to an equipotent chiral metabolite, diacetolol (DC). In this paper we report a case of a 32 year old woman who was receiving AC during her pregnancy and lactating time for management of hypertension. The maternal plasma level and breast milk as well as c...
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Four treatments were assigned to determine the effects of dietary potential digestible fiber (pdF) and crude protein (CP) levels in mid lactating Holstein cows on milk production and nitrogen efficiency. Sixteen primiparous (n=8) and multiparous (n=8) Holstein cows (body weight (BW)=546±72 kg; days in milk (DIM)=118±50 day) were allocated to one of four diets in balanced randomized complete des...
متن کاملBreast feeding and anaesthesia.
Anaesthetists require a good knowledge of the excretion of drugs in breast milk and the potential hazards to suckling infants of drug ingestion via breast milk. A brief account of the physiology of lactation is given. The mechanisms of drug passage into breast milk are discussed followed by a review of the excretion in breast milk of drugs used in anaesthetic practice. Suggestions for the manag...
متن کاملExcretion rate of progesterone in milk and faeces in lactating dairy cows with two levels of milk yield.
This study was conducted to measure the effect of the level of daily milk yield on the excretion rate of progesterone (P4) in milk and faeces in high-producing (HP) and low-producing (LP) lactating dairy cows. A GnRH-agonist was implanted to block endogenous production of P4. A CIDR device was inserted into the vagina and left in place for 11 days. The average and peak milk yields were greater ...
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عنوان ژورنال:
- Cancer
دوره 60 9 شماره
صفحات -
تاریخ انتشار 1987